Cerebral Palsy
Kind Note from Miami-based freelance writer and Chief Editor of Cerebral Palsy Guidance Alex Diaz-Granados.
I hope you're having a nice week and this email finds you in good health. I commend your work at Orchid, and I'm interested in talking about the possibility of working together in some capacity. |
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Pathogenesis of cerebral palsy through the prism of immune regulation of nervous tissue homeostasis: literature review
Abstract Background: The cerebral palsy is highly actual issue of pediatrics, causing significant neurological disability. Though the great progress in the neuroscience has been recently achieved, the pathogenesis of cerebral palsy is still poorly understood. Methods: In this work, we reviewed available experimental and clinical data concerning the role of immune cells in pathogenesis of cerebral palsy. Maintaining of homeostasis in nervous tissue and its transformation in case of periventricular leukomalacia were analyzed. Results: The reviewed data demonstrate involvement of immune regulatory cells in the formation of nervous tissue imbalance and chronicity of inborn brain damage. The supported opinion, that periventricular leukomalacia is not a static phenomenon, but developing process, encourages our optimism about the possibility of its correction. Conclusions: The further studies of changes of the nervous and immune systems in cerebral palsy are needed to create fundamentally new directions of the specific therapy and individual schemes of rehabilitation. |